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Eggman employed a number of Toxomisters during his first visit to Angel Island. While the Prime Zone was reshaped by the second Genesis Wave, a number of Toxomisters appeared aboard the Wily Egg while Sonic the Hedgehog and Mega Man were fighting their way through it to reach Eggman and Dr. Wily. (MM: #27)
- Toxomister first appeared in the game Sonic & Knuckles.
- Toxomister at Sonic News Network