- Given their name, it is likely that the Brass Knuckles are intended to be descendants of Knuckles the Echidna. Their name is also shared with the hand weapons.
- Whether intentional or not, the Brass Knuckles' mechanical nature makes them resemble the Cybermen of Doctor Who-fame.
- In the Off Panel for StH #243, a version of Metal Knuckles known as Brass Knuckles is featured. However, this version bears little resemblance to the Mobius Galaxy villains.